A Transition-Metal-Free One-Pot Cascade Process for Transformation of Primary Alcohols (RCH2OH) to Nitriles (RCN) Mediated by SO2F2

DOI: 10.1002/ejoc.201900478

Source and publish data:

European Journal of Organic Chemistry p. 3190 - 3194 (2019)

Update date:2022-09-26

Topics:

Authors:

Jiang, Ying

Sun, Bing

Fang, Wan-Yin

Qin, Hua-Li

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Article abstract of DOI:10.1002/ejoc.201900478

A new transition-metal-free one-pot cascade process for the direct conversion of alcohols to nitriles was developed without introducing an “additional carbon atom”. This protocol allows transformations of readily available, inexpensive, and abundant alcohols to highly valuable nitriles.

Full text of DOI:10.1002/ejoc.201900478

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