
Tetrahedron Letters p. 3043 - 3046 (1980)
Update date:2022-07-30
Topics:
Abenhafn, D.
Boireau, G.
Sabourault, B.
Lithium tetrabutylaluminate modified by either (-)-N-methylephedrine or Darvon alcohol (+)-(2S, 3R)-4-dimethylamino-3-methyl-1,2-diphenyl-2-butanol readily reacts with phenylglyoxylic acid methyl ester to give the expected α-butyl α-hydroxy ester with a good chemical yield and an optical yield of 43percent when Darvon alcohol is used.
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