Tetrahedron p. 955 - 962 (1985)
Update date:2022-08-02
Topics:
Renauld, Frank
Moreau, Serge
Lablache-Combier, Alain
Tiffon, Bernard
Botryodiplodin is a mycotoxin isolated from a strain of Penicillium roqueforti.This toxin exhibits genotoxic properties, it inhibits cell metabolism at the level of replication, transcription and traduction; it induces DNA-protein cross-links.The chemical reaction with amino-pyrimidines and amino-purine has led to 2-aminooxolane compounds.The structure and the stereochemistry of these adducts have been studied.Likewise the reaction with various 2'-deoxynucleosides has led to similar compounds.
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Doi:10.1039/jr9470000320
(1947)Doi:10.1055/s-1985-31174
(1985)Doi:10.1002/ardp.19853180705
(1985)Doi:10.1002/anie.202015004
(2021)Doi:10.1021/jo00223a003
(1985)Doi:10.1016/S0960-894X(02)00185-3
(2002)
