Journal of Organic Chemistry p. 4432 - 4439 (1985)
Update date:2022-08-02
Topics:
Baldwin, S. W.
Wilson, J. D.
Aube, J.
A series of 5-alkenyl and 6-alkenyl aldehydes bearing aryl and ester functionality on the alkene and with and without 1,3-dioxolane substitution at the 3-position has been prepared.The N-methyl and N-benzyl nitrones derived by the condensation of the aldehydes with the corresponding hydroxylamines undergo intramolecular 1,3-dipolar cycloaddition on heating (or at room temperature in two instances) to give either bridged or fused isoxazolidines depending on the regiochemistry of the cycloaddition reaction.The 6-alkenyl nitrones give fused products in all cases except those bearing an aryl group at C-6, which give bridged products.All of the 5-alkenyl nitrones prepared in this study cyclized to afford fused isoxazolidines.
View MoreContact:+86-574-89075960
Address:#100 Xiang Yun Road, New High tech area, Ningbo, China
Hangzhou Haiqiang Chemical Co.,Ltd.
Contact:+86-571-86960370
Address:Add: 5/F, Around Town North Road,No. 10, Hangzhou, Zhejiang,China
ShanDong XinDa Chemical CO.,LTD
Contact:086-0311-87580543
Address:No.168, High Technology Development Zone Jinan Shandong China
Contact:.+86-579-85566777
Address:12222222222dsadsdsdeeeee
JIANGXI ZHANGFENG CHEMICAL CO., LTD.
Contact:+86-0799-3413066
Address:Xiyuan village, Xiabu Town, Xiangdong District
Doi:10.1002/hlca.19860690111
(1986)Doi:10.1016/S0031-9422(00)81963-9
(1980)Doi:10.1021/bi00607a006
(1978)Doi:10.1039/jr9320001215
(1932)Doi:10.1021/om00132a022
(1986)Doi:10.1002/ejoc.201300777
(2013)