Tetrahedron Letters p. 2371 - 2374 (1986)
Update date:2022-07-30
Topics:
Tran, P. L.
Brienne, M. J.
Malthete, J.
Lacombe, L.
Pure fluorescent derivatives of 12-O-tetradecanoyl phorbol-13-acetate (TPA), labeled in the tetradecanoyl chain, are synthesized by two ways: 1) from both enantiomers of β-N-dansylaminotetradecanoic acid which requires the resolution of the (+/-)β-aminoacid precursor; 2) from an achiral fluorescent chain derived from 3-azatetradecanoic acid.The new phorbol derivatives retain the main biological activity of TPA.
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Doi:10.1055/s-1985-31122
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(1985)Doi:10.1007/BF00798462
(1985)Doi:10.1016/S0040-4020(01)93200-4
(1959)Doi:10.1016/0040-4020(59)85007-9
(1959)Doi:10.1246/bcsj.59.751
(1986)
