Tetrahedron Letters p. 1815 - 1818 (1985)
Update date:2022-08-04
Topics: Synthesis Chiral AcyloNucleoside Antiherpetic (S)-9-(2,3-Dihydroxy-1-Propoxymethyl)Guanine
MacCoss, Malcolm
Chen, Anna
Tolman, Richard L.
A new synthesis of the potential antiviral agent, (S)-9-(2,3-dihydroxy-1-propoxymethyl)guanine is described, starting from the readily available methyl 2,3,4-tri-O-benzyl-α-D-glucopyranoside.The sequence utilizes the absolute configuration defined by carb
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