
Tetrahedron p. 895 - 900 (1985)
Update date:2022-08-04
Topics: Cleavage Semisynthesis
Galpin, I. J.
Hoyland, D. A.
Methoxycarbonyl sulphenyl chloride (Scm.Cl) and o-nitrophenyl-sulphenyl chloride (Nps.Cl) have been shown to cleave methionyl peptide bonds in a manner similar to that found with cyanogen bromide.These new methods of cleavage of methionyl peptide bonds were illustrated by digestion of H.Gly.Met.Ala.OH trifluoroacetate, the (1-32) fragment of adrenocorticotropic hormone <(1-32) ACTH> and Hen Egg-White Lysozyme.
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