Concise synthesis of tetrahydro derivatives of the pyrido[2,3-b]acridine and pyrido[3,2-b]acridine ring systems

Article abstract of DOI:10.1016/S0040-4020(99)00738-3

5,6,7,8-Tetrahydro-1,4-acridinequinones were readily prepared by Friedlander reaction between cyclohexanone and 2-amino-3,6- dimethoxybenzaldehydes or 2-amino-3,6-dimethoxyacetophenones, followed by oxidative demethylation. Their Diels-Alder reactions wit