DMAP-catalyzed hydroxymethylation of 2-cyclohexenones in aqueous medium through baylis-hillman reaction

DOI: 10.1016/S0040-4039(98)01206-4

Source and publish data:

Tetrahedron Letters p. 5965 - 5966 (1998)

Update date:2022-08-04

Topics:

Authors:

Rezgui, Farhat

El Gaied, Mohamed Moncef

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Article abstract of DOI:10.1016/S0040-4039(98)01206-4

Reaction of 2-cyclohexenones 1a-d with aqueous formaldehyde, catalyzed by DMAP in THF, affords the corresponding 2-(hydroxymethyl)-2-cyclohexenones 2a-d in good yields.

Full text of DOI:10.1016/S0040-4039(98)01206-4

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