Synthesis and biological activity of certain nucleoside and nucleotide derivatives of pyrazofurin

DOI: 10.1021/jm00152a016

Source and publish data:

Journal of Medicinal Chemistry p. 268 - 278 (1986)

Update date:2022-08-05

Topics:

Authors:

Petrie III.

Revankar

Dalley Dalley

George George

McKernan

Hamill Hamill

Robins Robins

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Article abstract of DOI:10.1021/jm00152a016

A number of nucleoside and nucleotide derivatives of 4-hydroxy-3-β-D-ribofuranosylpyrazole-5-carboxamide (pyrazofurin, 1) were prepared and tested for their antiviral and cytostatic activity in cell culture. Treatment of 1 with benzyl bromide gave 4-O-ben

Full text of DOI:10.1021/jm00152a016

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