Zwitterionic Analogues of Cimetidine as H2 Receptor Antagonists

DOI: 10.1021/jm00390a006

Source and publish data:

Journal of Medicinal Chemistry p. 1150 - 1156 (1987)

Update date:2022-07-29

Topics:

Authors:

Young, Rodney C.

Ganellin, C. Robin

Graham, Michael J.

Mitchell, Robert C.

Roantree, Michael L.

Tashma, Zev

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Article abstract of DOI:10.1021/jm00390a006

A series of analogues of the H₂ receptor histamine antagonist cimetidine have been synthesized in which the dipolar cyanoguanidine group has been replaced by a number of zwitterionic moieties.Although none of the compounds is more effective tha

Full text of DOI:10.1021/jm00390a006

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