Zwitterionic Analogues of Cimetidine as H2 Receptor Antagonists

DOI: 10.1021/jm00390a006

Source and publish data:

Journal of Medicinal Chemistry p. 1150 - 1156 (1987)

Update date:2022-07-29

Topics:

Authors:

Young, Rodney C.

Ganellin, C. Robin

Graham, Michael J.

Mitchell, Robert C.

Roantree, Michael L.

Tashma, Zev

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00390a006

A series of analogues of the H₂ receptor histamine antagonist cimetidine have been synthesized in which the dipolar cyanoguanidine group has been replaced by a number of zwitterionic moieties.Although none of the compounds is more effective tha

Full text of DOI:10.1021/jm00390a006

Products guided by the article

Product name:N-methyl-4-hydroxybenzamidine

Cas No:99463-01-1

R&D Labs maybe for 99463-01-1

WEIFANG RICHEM INTERNATIONAL LTD

Contact:86-536-2222176

Address:weifang,shandong
Jingzhou TianHe Sci&Tech Chemical Co., Ltd.

Contact:86-716-8331612

Address:Jiangjin Road, #18, High-grade technology industries development district, Jingzhou city, Hubei province
Zhejiang kehong chemical co., ltd

Contact:0086-575-85522000

Address:xiner center RD binhai industrial zone shaoxing zhejiang province P.R.China,312073
Shantou Baokang Pharmaceutical Co., Ltd.

Contact:+86-754-88873487

Address:5/F B Block Huangshan Bldg Huangshan Rd Shantou
Onlychem (Jinan)Biotech Co.,Ltd

Contact:86-531-83175885

Address:No. 44, Honglou South Road, Jinan,China

Relevant to this article

Studies on the alkaloids from Picrasma quassioides BENNET. V. Structures of picrasidines L, M, and P

Doi:10.1248/cpb.33.3847
(1985)
The kinetics and mechanism of solvolysis of amineboranes

Doi:10.1021/ic50013a027
(1964)
Doi:10.1016/S0020-1693(00)83613-0
(1984)
Insertion of pyridine into an iron-silicon bond and photochemical conversion of the insertion product Cp*(OC)Fe{η³(C,C,C)- C₅H₅NSiMe₂NPh₂} to a sandwich compound

Doi:10.1021/om060873n
(2006)
Catalytic Enantioselective Synthesis of 3,4,5-Trisubstituted Isoxazoline N-Oxides and Regioselective Synthesis of 3,4,5-Trisubstituted Isoxazoles

Doi:10.1002/ejoc.201801693
(2019)
Synthesis, characterization, crystal structure, and theoretical studies on Schiff-base compound 6-[(5-Bromopyridin-2-yl)iminomethyl]phenol

Doi:10.1007/s11224-009-9554-5
(2010)

Article Doi