Journal of Medicinal Chemistry p. 1150 - 1156 (1987)
Update date:2022-07-29
Topics:
Young, Rodney C.
Ganellin, C. Robin
Graham, Michael J.
Mitchell, Robert C.
Roantree, Michael L.
Tashma, Zev
A series of analogues of the H2 receptor histamine antagonist cimetidine have been synthesized in which the dipolar cyanoguanidine group has been replaced by a number of zwitterionic moieties.Although none of the compounds is more effective tha
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