Preparation and antiarthritic activity of new 1,5-diaryl-3-alkylthio-1H-1,2,4-triazoles and corresponding sulfoxides and sulfones

DOI: 10.1016/0223-5234(90)90015-U

Source and publish data:

European Journal of Medicinal Chemistry p. 95 - 101 (1990)

Update date:2022-08-05

Topics:

Authors:

Szilagyi, Geza

Somorai, Tamas

Bozo, Eva

Lango, Jozsef

Nagy, Gabor

et al. et al.

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Article abstract of DOI:10.1016/0223-5234(90)90015-U

A series of 1,5-diaryl-3-alkylthio-1H-1,2,4-triazoles and corresponding sulfoxides and sulfones was synthesized and evaluated as antiinflammatory agents in the rat adjuvant induced arthritis assay.Several analogues were found to be more potent than phenyl

Full text of DOI:10.1016/0223-5234(90)90015-U

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