Synthesis and Inhibition of Human Acrosin and Trypsin and Acute Toxicity of Aryl 4-Guanidinobenzoates

DOI: 10.1021/jm00154a015

Source and publish data:

Journal of Medicinal Chemistry p. 514 - 519 (1986)

Update date:2022-08-05

Topics: Synthesis Trypsin Experimental Inhibition Acute Toxicity

Authors:

Kaminski, J. M.

Bauer, L.

Mack, S. R.

Anderson, R. A.

Waller, D. P.

Zaneveld, L. J. D.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00154a015

The aryl 4-guanidinobenzoate, 4'-nitrophenyl 4-guanidinobenzoate (NPGB), is potent inhibitor of sperm acrosin, an enzyme with an essential function in the fertilization process.NPGB prevents fertilization in a number of animal species and is a good lead c

Full text of DOI:10.1021/jm00154a015

Products guided by the article

Product name:4-Guanidino-benzoic acid 4-chloro-phenyl ester; compound with toluene-4-sulfonic acid

Cas No:99966-57-1

R&D Labs maybe for 99966-57-1

Changzhou Ansciep Chemical Co.,Ltd.

Contact:+86 519 8630 5871

Address:A-710 Boan International, 8 East Guangdian Road,Wujin,Changzhou
Chengda Pharmaceuticals Co., Ltd.

Contact:+86-573-84601188

Address:hengshan Road 5# in Jiashan, zhejiang
Chuzhou Baiao Biologhy S&T Co., Ltd.

Contact:+86-25-83212599；+86-25-83212699 13705185959

Address:Room 905, Tianzheng International Platza, No.399, Zhongyang Road ,Nanjing, Jiangsu Province, China
WUXI HONOR SHINE CHEMICAL CO.,LTD

Contact:+86-510-83593312

Address:No.1699 Huishan avenue,Huishan district,Wuxi ,Jiangsu,China,214177.(Wuxi Huishan Ecomonic Develop Zone )
TIANJIN FESTO CHEMICAL CO.,LTD(expird)

Contact:86-22-25814570

Address:No.12th,5th Ave.,TEDA,Tianjin,China

Relevant to this article

Group 4 metal complexes of fhiorous (Di)alkoxide-(Di)imino ligands: synthesis, structure, olefin polymerization catalysis, and decomposition pathways

Doi:10.1021/om8009409
(2009)
Chiral Chromium Salen@rGO as Multipurpose and Recyclable Heterogeneous Catalyst

Doi:10.1002/chem.202101003
(2021)
Reaction of Ethyl (E)-3-Methoxy-2-butenoate with Some Substituted Aromatic Aldehydes: Synthesis of 5-Aryl-3-Methoxy-(2E,4E)-2,4-Pentadienoic Acids

Doi:10.1055/s-1987-28038
(1987)
4-(4-Chloro-benzyl-idene-hydrazono-methyl)-benzonitrile and the bromo and iodo analogs

Doi:10.1107/S0108270107065171
(2008)
Doi:10.1021/jo01104a007
(1958)
Specific features of the reactions of quinazoline and its 4-hydroxy and 4-chloro substituted derivatives with C-nucleophiles

Doi:10.1016/j.tetlet.2009.03.199
(2009)

Article Doi