Journal of Medicinal Chemistry p. 514 - 519 (1986)
Update date:2022-08-05
Topics: Synthesis Trypsin Experimental Inhibition Acute Toxicity
Kaminski, J. M.
Bauer, L.
Mack, S. R.
Anderson, R. A.
Waller, D. P.
Zaneveld, L. J. D.
The aryl 4-guanidinobenzoate, 4'-nitrophenyl 4-guanidinobenzoate (NPGB), is potent inhibitor of sperm acrosin, an enzyme with an essential function in the fertilization process.NPGB prevents fertilization in a number of animal species and is a good lead c
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