Synlett p. 976 - 978 (2010)
Update date:2022-08-29
Topics:
Maurer, Stefan
Liu, Wei
Zhang, Xiaojing
Jiang, Yongwen
Ma, Dawei
The CuI/8-hydroxyquinoline-catalyzed direct hydroxylation of aryl iodides with KOH takes place at 100 C in a mixed solvent system (t-BuOH-DMSO-H 2O), providing the corresponding phenols in great diversity. Aryl bromides are found to be rather less reactive under these reaction conditions. Georg Thieme Verlag Stuttgart - New York.
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