Tetrahedron Letters p. 1625 - 1628 (1995)
Update date:2022-08-11
Topics:
Bolm, Carsten
Mueller, Peter
A chiral titanium reagent derived from optically active sulfoximine (R)-3 and Ti(O-i-Pr)4 promotes the asymmetric addition of trimethylsilylcyanide to aldehydes affording cyanohydrins in high yields with good enantioselectivities (up to 91% ee).
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