Tetrahedron p. 14477 - 14486 (1998)
Update date:2022-08-11
Topics:
Griengl, Herfried
Klempier, Norbert
Poechlauer, Peter
Schmidt, Michael
Shi, Nongyuan
Zabelinskaja-Mackova, Antonina A.
By employing a vigorously stirred two phase system aqueous buffer/organic solvent and using the hydroxynitrile lyase from Hevea brasiliensis as biocatalyst enantiopure (S)-cyanohydrins from aliphatic, unsaturated, aromatic and heteroaromatic aldehydes and methyl alkyl and methyl phenyl ketones are obtained in high yield and in general 98-99% enantiomeric excess.
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