Tetrahedron p. 3531 - 3540 (1999)
Update date:2022-08-30
Topics:
Lin, Guoqiang
Han, Shiqing
Li, Zuyi
The enantioselective synthesis of optically active (R)-cyanohydrins generated from several aromatic, heteroaromatic and aliphatic aldehydes and methyl ketones was carried out using almond, peach or loquat meal as (R)-oxynitrilase sources in diisopropylether under micro-aqueous conditions The micro-aqueous reaction system, which is superior to the conventionally used water-organic biphase reaction system, performed well over the temperature range of 4 deg C to 30 deg C.
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Doi:10.1002/hlca.19630460109
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