Asymmetric synthesis of tetronic acids by Blaise reaction of protected optically active cyanohydrins

Article abstract of DOI:10.1016/0957-4166(96)00059-6

An asymmetric synthesis of tetronic acids is described, involving the Blaise reaction of Reformatsky reagents with silyl-protected optically active cyanohydrins, which were prepared by an enzyme-catalysed method.