Enantioselective addition of diethylzinc to aromatic aldehydes catalysed by chiral ligands derived from L-hydroxyproline

Article abstract of DOI:10.1080/00397919308013799

The lithium salts of chiral auxiliaries 2-4 derived from L-hydroxyprolin (2S,4R)-1 catalysed the enantioselecive addition of diethylzinc to aromatic aldehydes to afford sec alcohols in up to 80% optical purity.

Full text of DOI:10.1080/00397919308013799

This article was downloaded by: [University of Kiel]
On: 26 October 2014, At: 05:49
Publisher: Taylor & Francis
Informa Ltd Registered in England and Wales Registered Number: 1072954
Registered office: Mortimer House, 37-41 Mortimer Street, London W1T 3JH,
UK
Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
Publication details, including instructions for
authors and subscription information:
http://www.tandfonline.com/loi/lsyc20
Enantioselective Addition
of Diethylzinc to Aromatic
Aldehydes Catalysed by Chiral
Ligands Derived from L-
Hydroxyproline
a
a
Thomas Mehler , Jürgen Martens & Sabine
a
Wallbaum
a
Fachbereich Chemie , Universität Oldenburg ,
Ammerl änder Heerstraß Ze 114-118, D-2900,
Oldenburg i.O., Germany
Published online: 23 Sep 2006.
To cite this article: Thomas Mehler , Jürgen Martens & Sabine Wallbaum (1993)
Enantioselective Addition of Diethylzinc to Aromatic Aldehydes Catalysed by Chiral
Ligands Derived from L-Hydroxyproline, Synthetic Communications: An International
Journal for Rapid Communication of Synthetic Organic Chemistry, 23:19, 2691-2699,
DOI: 10.1080/00397919308013799
To link to this article: http://dx.doi.org/10.1080/00397919308013799
PLEASE SCROLL DOWN FOR ARTICLE
Taylor & Francis makes every effort to ensure the accuracy of all the
information (the “Content”) contained in the publications on our platform.
However, Taylor & Francis, our agents, and our licensors make no
representations or warranties whatsoever as to the accuracy, completeness,

or suitability for any purpose of the Content. Any opinions and views
expressed in this publication are the opinions and views of the authors, and
are not the views of or endorsed by Taylor & Francis. The accuracy of the
Content should not be relied upon and should be independently verified with
primary sources of information. Taylor and Francis shall not be liable for any
losses, actions, claims, proceedings, demands, costs, expenses, damages,
and other liabilities whatsoever or howsoever caused arising directly or
indirectly in connection with, in relation to or arising out of the use of the
Content.
This article may be used for research, teaching, and private study purposes.
Any substantial or systematic reproduction, redistribution, reselling, loan,
sub-licensing, systematic supply, or distribution in any form to anyone is
expressly forbidden. Terms & Conditions of access and use can be found at
http://www.tandfonline.com/page/terms-and-conditions