Tetrahedron p. 1471 - 1490 (1998)
Update date:2022-08-11
Topics:
Jones, Philip
Kishan Reddy
Knochel, Paul
Functionalised mixed alkyl(trimethylsilylmethyl)zinc reagents add efficiently to a wide variety of Michael acceptors in high yield and with exclusive 1,4-regioselectivity, without the need for transition metal catalysis. The trimethylsilylmethyl group behaves as a non-transferable group, and in no cases was transfer of this group observed.
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