Journal of Polymer Science, Part A: Polymer Chemistry p. 321 - 329 (2014)
Update date:2022-08-10
Topics:
Lin, Yung-Chih
Kuo, Shiao-Wei
In this study, we used click chemistry to synthesize new linear polypeptide-g-pyrene polymers from a mono-azido-functionalized pyrene derivative (N3-Py) and several poly(γ-propargyl-l-glutamate) (PPLG) oligomers. Incorporating the pyrene units as side chains enhanced the α-helical conformations of these PPLG oligomers in the solid state, as determined using Fourier transform infrared (FTIR) spectroscopy; it also increased the temperature stability of the α-helical secondary structures of the grafted PPLG oligomers, relative to those of the pure PPLG species, as revealed through temperature-dependent FTIR spectroscopic analyses. In addition, the thermal properties of the PPLG-g-Py polypeptides (e.g., glass transition temperatures increased by ca. 100 °C) were superior to those of pure PPLG oligomers. Mixing the PPLG-g-Py oligomers with multiwalled carbon nanotubes (MWCNTs) in dimethylformamide led to the formation of highly dispersible PPLG-g-Py/MWCNT organic/inorganic hybrid complex materials. Fluorescence emission spectra revealed significant π-π stacking between the PPLG-g-Py oligomers and the MWCNTs in these complexes. 2013 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2014, 52, 321-329 Click chemistry is used to synthesize new linear polypeptide-g-pyrene polymers from a mono-azido-functionalized pyrene derivative (N3-Py) and several poly(γ-propargyl-l-glutamate) (PPLG) oligomers. Incorporating the pyrene units as side chains enhances the α-helical conformations of these PPLG oligomers in the solid state and increases the temperature stability of the α-helical secondary structures of the grafted PPLG oligomers, relative to those of the pure PPLG species. Copyright
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Doi:10.1002/poc.1569
(2009)Doi:10.1007/s00044-019-02395-5
(2019)Doi:10.3184/174751916X14495860660659
(2016)Doi:10.1021/jo01093a625
(1959)Doi:10.1039/c19670000993
()Doi:10.1248/cpb.10.753
(1962)