Chemical and Pharmaceutical Bulletin p. 356 - 358 (1995)
Update date:2022-08-16
Topics:
Tanaka
Kagechika
Shudo
Treatment of retinoic acid (1a) or its methyl ester (2a) with hydrochloric acid in methanol gave methyl 4-oxo-retinoates (4a - c). Similar oxidation proceeded when 2a was treated with trifluoromethanesulfonic acid in the presence of lithium chloride in methanol.
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