Site-Specific Synthesis of Carbazole Derivatives through Aryl Homocoupling and Amination

Article abstract of DOI:10.1055/s-0039-1690759

We synthesized various carbazoles from anilines through a three-step process with good overall yields (up to 48percent). This process comprises N -acetylation, copper(0)-mediated Ullmann homocoupling, and acid-mediated intramolecular amination. It permits various functional groups on the substrate. Scale-up of the developed three-step synthetic route to carbazoles was also demonstrated.