Michael-type reactions of tenulin, a biologically active sesquiterpene lactone

DOI: 10.1002/jps.2600721228

Source and publish data:

Journal of Pharmaceutical Sciences p. 1474 - 1476 (1983)

Update date:2022-08-10

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Authors:

Waddell Waddell

Gebert Gebert

Tait Tait

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Article abstract of DOI:10.1002/jps.2600721228

The antitumor pseudoguainolide tenulin has been exposed to a wide variety of biological and model nucleophilic reagents and has been shown to react exclusively with sulfur nucleophiles in a Michael-like fashion. The biological implications of these results are discussed.

Full text of DOI:10.1002/jps.2600721228

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