Solid Superacid-Catalyzed Organic Synthesis. 4. Perfluorinated Resinsulfonic Acid (Nafion-H) Catalyzed Friedel-Crafts Benzylation of Benzene and Substituted Benzenes

Article abstract of DOI:10.1021/jo00006a023

Nafion-H, a perfluorinated resinsulfonic acid, catalyzes Friedel-Crafts benzylation of benzene and substituted benzenes with benzyl alcohols under relatively mild experimental conditions.Reactions are clean, and water formed as a byproduct does not deactivate the catalyst.It was also found that this method is applicable to the intramolecular cycloalkylation and oligomerization of methoxybenzyl alcohols.