Synthesis of aminoethanethiol trityl ether ligands for ruthenium-catalysed asymmetric transfer hydrogenation

Article abstract of DOI:10.1016/j.tetasy.2004.08.017

A series of chiral aminoethanethiol ethers was synthesised by the regioselective and stereospecific ring opening of the (R)- trityl(thiiranylmethyl)ether and examined in the hydrogen transfer reduction of different aromatic ketones. High conversions (>99%