Hydrolysis of Mustard Derivatives. Remarkable Tosylate/Chloride and Chloride/Dinitrophenolate Rate Ratios

DOI: 10.1016/S0040-4039(00)98754-9

Source and publish data:

Tetrahedron Letters p. 4571 - 4574 (1985)

Update date:2022-08-16

Topics:

Authors:

McManus, S. P.

Neamati-Mazreah, N.

Paley, M. S.

Hovanes, B. A.

Harris, J. M.

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Article abstract of DOI:10.1016/S0040-4039(00)98754-9

Comparisons of leaving group solvolytic rate ratios for mustard derivatives with other substrate types reveals unusual OTs/Cl and Cl/ODNP rate ratios for mustards.A very tight transition state is suggested.

Full text of DOI:10.1016/S0040-4039(00)98754-9

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