Synthesis of DNA Containing Modified Bases by Postsynthetic Substitution. Synthesis of Oligomers Containing 4-Substituted Thymine: O4-Alkylthymine, 5-Methylcytosine, N4-(Dimethylamino)-5-methylcytosine, and 4-Thiothymine

DOI: 10.1021/jo00040a024

Source and publish data:

Journal of Organic Chemistry p. 3839 - 3845 (1992)

Update date:2022-08-11

Topics:

Authors:

Xu, Yao-Zhong

Zheng, Qinguo

Swann, Peter F.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00040a024

A strategy is described for synthesis of oligomers modified in the 4-position of thymine by postsynthetic substitution. 4-Triazolothymine phosphoramidite monomer has been prepared in one step from thymine amidite monomer and incorporated into a 12 mer AGC

Full text of DOI:10.1021/jo00040a024

Products guided by the article

Product name:(2R,3S,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-5-(5-METHYL-2-OXO-4-(1H-1,2,4-TRIAZOL-1-YL)PYRIMIDIN-1(2H)-YL)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE

Cas No:101712-10-1

R&D Labs maybe for 101712-10-1

Jai Radhe Sales

website:http://www.jairadhesales.com

Contact:0091-79-26431096

Address:309 Harikrupa Tower,Nr old Sharda Mandir Char Rasta,Ellisbridge
taicang liyuan chemical co,.ltd

website:http://www.tcliyuanchem.com/productse.php

Contact:86-512-53539583

Address:Room 804,Huaxu Building,No.95,Renmin South Road,Taicang city,Jiangsu Province,China
Hybio Pharmaceutica Co.,Ltd

website:http://www.hybio.com.cn

Contact:+86 755 26588093

Address:No.9 Linkong West Street, Hengdian Street, Huangpi District, Wuhan City, China.
Chongqing Yawei Fine Chemical Co.,Ltd

Contact:0086-23-62849407

Address:Ziyou village, Nanquan town, Banan district, Chongqing China
Advanced Biotech

Contact:+1-973-357-0577

Address:10 Taft Rd.

Relevant to this article

5,6-Dihydroxyindole-2-carboxylic acid, a diffusible melanin precursor, is a potent stimulator of lipopolysaccharide-induced production of nitric oxide by J774 macrophages

Doi:10.1016/0024-3205(95)02244-2
(1995)
Photocatalyzed Csp³-Csp³cross-dehydrogenative coupling of: N -Boc-tetrahydroisoquinolines with α,β-unsaturated ketones

Doi:10.1039/d1ob00527h
(2021)
Synthesis of 5,12-Diazapentacenes and Their Properties

Doi:10.1021/acs.joc.9b01628
(2019)
Theoretical Study of Intramolecular Aldol Condensation of 1,6-Diketones: Trimethylsilyl Substituent Effect

Doi:10.1021/jo005544y
(2000)
2,3:4,5-DI-O-isopropylidene-β-D-fructopyranose as chiral auxiliary in asymmetric α-alkylation of ester enolates

Doi:10.1080/07328309608005685
(1996)
NOVEL INSERTION REACTIONS INTO CYCLIC TIN-OXYGEN COMPOUNDS

Doi:10.1016/S0022-328X(00)95255-0
(1982)

Article Doi