An Efficient One-Pot Preparation of 2,4-Pentadienoic Esters from α,β-Unsaturated Aldehydes

Article abstract of DOI:10.1055/s-1988-27626

α,β-Unsaturated aldehydes react with monoalkyl malonates in pyridine with a catalytic amount of dimethylaminopyridine (DMAP) in a regio- and stereoselective process to yield almost exclusively 2,4-pentadienoic esters with essentially (and in many cases exclusively) the 2E-stereochemistry.