Monatshefte fur Chemie p. 1003 - 1008 (2018)
Update date:2022-08-11
Topics:
Yang, Yunxia
Zhang, Di
Xu, Mengsheng
Wang, Jianhong
Chen, Jipeng
Wang, Le
Abstract: A fluorescent probe 4-amino-7-nitrobenz-2-oxa-1,3-diazole NBD–NH2 for critical sensing hypochlorous (ClO?) has been developed in this paper. Probe NBD–NH2 exhibited excellent sensitivity and high selectivity toward detection of ClO? in CH3CH2OH/HEPES solution (1:4, v/v, 10?mM, pH 7.4), where the detection limit as low as 40?nM. The green fluorescence of NBD–NH2 was distinctly quenched by addition of ClO?. In addition, the new probe was also applied for bioimaging using HeLa cells and exist a critical detection of ClO? in living cells. Graphical abstract: [Figure not available: see fulltext.].
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