Tetrahedron Letters p. 4265 - 4268 (1985)
Update date:2022-08-11
Topics:
Harnden, M.R.
Jarvest, R.L.
Alkylation of 2-amino-6-chloropurine with 5-(2-bromoethyl)-2,2-dimethyl-1,3-dioxan (7) and subsequent acid hydrolysis provides an improved procedure for synthesis of the antiviral acyclonucleoside 9-(4-hydroxy-3-hydroxymethylbut-1-yl)guanine (3).
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