Catalytic asymmetric Mukaiyama aldol reactions in aqueous media

DOI: 10.1016/S0040-4020(99)00440-8

Source and publish data:

Tetrahedron p. 8739 - 8746 (1999)

Update date:2022-08-11

Topics:

Authors:

Kobayashi, Shu

Nagayama, Satoshi

Busujima, Tsuyoshi

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Article abstract of DOI:10.1016/S0040-4020(99)00440-8

Chiral copper(II)-catalyzed asymmetric aldol reactions of silyl enol ethers with aldehydes (the Mukaiyama aldol reaction) have been performed in an ethanol-water solution. The use of the protic solvent including water is a key to achieve these reactions.

Full text of DOI:10.1016/S0040-4020(99)00440-8

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