
Tetrahedron p. 8739 - 8746 (1999)
Update date:2022-08-11
Topics:
Kobayashi, Shu
Nagayama, Satoshi
Busujima, Tsuyoshi
Chiral copper(II)-catalyzed asymmetric aldol reactions of silyl enol ethers with aldehydes (the Mukaiyama aldol reaction) have been performed in an ethanol-water solution. The use of the protic solvent including water is a key to achieve these reactions.
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Doi:10.1016/S0040-4020(01)86490-5
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(1952)