Samarium Diiodide Mediated Alkylation of Saturated Heterocycles alpha to Nitrogen

DOI: 10.1016/0040-4020(95)00081-I

Source and publish data:

Tetrahedron p. 3665 - 3674 (1995)

Update date:2022-08-17

Topics:

Authors:

Booth, Susan E.

Benneche, Tore

Undheim, Kjell

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4020(95)00081-I

A method for α-alkylation of saturated 5-, 6-, 7- and 8-membered aza-heterocycles is described.The auxiliary is an o-iodobenzyl group attached at the nitrogen.A radical introduced in the o-position is transferred to the amine α-position which subsequently leads to an addition reaction with pentan-3-one.

Full text of DOI:10.1016/0040-4020(95)00081-I

Products guided by the article

Product name:4-benzylmorpholine

Cas No:10316-00-4

R&D Labs maybe for 10316-00-4

SICHUAN ZHONGBANG NEW MATERIAL CO., LTD

website:http://www.zhongbangst.com

Contact:86-830-2585019

Address:sichuan,china
Yangzhou Siyu Chemical Co.,Ltd.

Contact:+86-514-87325867 13358126196

Address:Room 620 Exposition Pavilion，No. 98 Huaihai Road,Guangling District，Yangzhou City, Jiangsu Province
Acorn PharmaTech Co., Ltd

Contact:86-25-58619180

Address:Nanjing High-Tech Zone 10 Xinghuo Road Pukou District Nanjing, Jiangsu 210061 The People's Republic of China
MS( MAOSHENG )Chemical CO.,LTD

Contact:+86-519-82726678.82726378

Address:TAOXI INDUSTRY ZONE JINTAN
Goldwills Pharmaceuticals Co., Ltd.

Contact:0916-2237889 13991621155

Address:North Suburb of Hanzhong city, Shaanxi Province

Relevant to this article

Bi (NO₃)₃·5H₂O and cellulose mediated Cu-NPs - A highly efficient and novel catalytic system for aerobic oxidation of alcohols to carbonyls and synthesis of DFF from HMF

Doi:10.1016/j.catcom.2016.01.003
(2016)
Altering the polymorphic product distribution in a solid-state dehydration process by rapid sample rotation in a solid-state NMR probe

Doi:10.1021/ja052668p
(2005)
Metal-Free Radical Borylation of Alkyl and Aryl Iodides

Doi:10.1002/anie.201810782
(2018)
Doi:10.1063/1.1668253
(1968)
An Inverse Reactivity-Selectivity Relationship. Kinetic Nitrogen Isotope Effects on Methyl Transfer to Pyridines

Doi:10.1021/ja00385a062
(1982)
Design, synthesis, and evaluation of transition-state analogs as inhibitors of the bacterial quorum sensing autoinducer synthase CepI

Doi:10.1016/j.bmcl.2021.127873
(2021)

Article Doi