Resolution of prenyl bromohydrin esters and derivatives: Synthesis of the quinoline alkaloid (+)-(R)- and (-)-(S)-lunacridine

DOI: 10.1016/S0040-4020(01)89424-2

Source and publish data:

Tetrahedron p. 11219 - 11234 (1994)

Update date:2022-07-29

Topics:

Authors:

Barr Barr

Boyd Boyd

Sharma Sharma

Evans Evans

Malone Malone

Mehta Mehta

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Article abstract of DOI:10.1016/S0040-4020(01)89424-2

Chromatographic separation of the bromohydrin MTPA diastereoisomers formed at the prenyl group attached to quinoline and coumarin rings is reported; base catalysed cyclization of the bromo MTPA esters in the quinoline series yielded the corresponding pren

Full text of DOI:10.1016/S0040-4020(01)89424-2

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