Lithium enediolates and dienediolates of carboxylic acids in synthesis: Alkylation with secondary halides

Article abstract of DOI:10.1016/S0040-4020(98)00957-0

High yields in the alkylation of dianions of α,β-unsaturated carboxylic acids with secondary halides can be obtained despite elimination reactions occurring. α-Regioselectivity for the alkylation of but-2-enoic acids (1-4) is seldom obtained. Although dou