One-pot, solvent free synthesis of hantzsch 1, 4-dihydropyridines using β-cyclodextrin as a supramolecular catalyst

Article abstract of DOI:10.2174/157017811796504891

A novel, solvent free and efficient one pot synthesis of 1, 4-dihydropyridine derivatives was achieved in good yields via three component reaction of aldehydes, ethyl acetoacetate and ammonium acetate using inexpensive β- cyclodextrin as a supramolecular catalyst. The catalyst can be recovered and reused without loss of activity.