Synthetic Communications p. 3149 - 3155 (1993)
Update date:2022-08-16
Topics:
Balicki
Kaczmarek
The urea-hydrogen peroxide adduct, an inexpensive, stable and easily handled reagent has shown utility for mild and efficient transformation of nitriles into the corresponding aliphatic or aromatic amides. Reaction proceeds in aqueous acetone, within 0.5-2. 5h, in the presence of catalytic amount of K2CO3, at room temperature.
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Doi:10.1007/BF01517080
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