Mild and efficient conversion of nitriles to amides with basic urea- hydrogen peroxide adduct

Article abstract of DOI:10.1080/00397919308011173

The urea-hydrogen peroxide adduct, an inexpensive, stable and easily handled reagent has shown utility for mild and efficient transformation of nitriles into the corresponding aliphatic or aromatic amides. Reaction proceeds in aqueous acetone, within 0.5-2. 5h, in the presence of catalytic amount of K₂CO₃, at room temperature.

Full text of DOI:10.1080/00397919308011173

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Synthetic Communications: An
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Organic Chemistry
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Mild and Efficient Conversion
of Nitriles to Amides with
Basic Urea-Hydrogen Peroxide
Adduct
a
a
Roman Balicki & Łukasz Kaczmarek
a
Institute of Organic Chemistry Polish Academy of
Sciences, Kasprzaka 44/52, PL-01-224, Warszawa,
Poland
Version of record first published: 23 Sep 2006.
To cite this article: Roman Balicki & Łukasz Kaczmarek (1993): Mild and Efficient
Conversion of Nitriles to Amides with Basic Urea-Hydrogen Peroxide Adduct, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 23:22, 3149-3155
To link to this article: http://dx.doi.org/10.1080/00397919308011173
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