Synthesis p. 40 - 42 (1987)
Update date:2022-08-17
Topics:
Frejd, Torbjoern
Klingstedt, Tomas
Arylacetonitriles are synthesised by coupling arylzinc chlorides with bromoacetonitrile using Ni(acac)2/P(c-C6H11)(C6H5)2 as catalyst.The arylacetonitriles are reduced in situ with LiAlH4/AlCl3 to give the corresponding 2-aryl-1-aminoethanes.
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Doi:10.1124/dmd.110.037663
(2011)Doi:10.1039/c2dt30190c
(2012)Doi:10.1039/c8gc03498b
(2019)Doi:10.1002/jlcr.1204
(2007)Doi:10.1002/hlca.19860690117
(1986)Doi:10.1139/v67-021
(1967)
