Mild reduction of carboxylic acids to alcohols using cyanuric chloride and sodium borohydride

DOI: 10.1016/S0040-4039(99)00734-0

Source and publish data:

Tetrahedron Letters p. 4395 - 4396 (1999)

Update date:2022-08-11

Topics:

Authors:

Falorni, Massimo

Porcheddu, Andrea

Taddei, Maurizio

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Article abstract of DOI:10.1016/S0040-4039(99)00734-0

Several carboxylic acids, including N-Boc, N-Cbz and N-Fmoc amino acids were reduced to the corresponding alcohols by activation of the carboxy function with cyanuric chloride and N-methylmorpholine followed by reduction with aqueous sodium borohydride.

Full text of DOI:10.1016/S0040-4039(99)00734-0

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