Mild reduction of carboxylic acids to alcohols using cyanuric chloride and sodium borohydride

Article abstract of DOI:10.1016/S0040-4039(99)00734-0

Several carboxylic acids, including N-Boc, N-Cbz and N-Fmoc amino acids were reduced to the corresponding alcohols by activation of the carboxy function with cyanuric chloride and N-methylmorpholine followed by reduction with aqueous sodium borohydride.