Synthetic Communications p. 907 - 913 (1995)
Update date:2022-08-18
Topics:
Hu
Cassady
A simple and one-step method has been developed for selective O-benzylation of aminoalkanols. Study of steric effects shows the best selectivity in adjacent 1°-OH vs 2°-CHNH2 and decreased selectivity in 2°-OH vs 1°-CH2NH2 and non adjacent aminoalkanol.
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