Syntheses and evaluation of benzodiazaborine compounds against M. tuberculosis H37R(v) in vitro

Article abstract of DOI:10.1016/S0960-894X(98)00126-7

The synthesis of six benzo[e]diazaborine compounds and their in vitro evaluation against M. tuberculosis H₃₇R(v) is described. The compounds 1,2-dihydro-1-hydroxy-2-phenyl-2,4,1-benzo[e]diazaborin-3(4H)-one, 4, and 1,2-dihydro-1-hydroxy-2-(3-pyridyl)-2,4,1-benzo[e]diazaborin-3(4H)-thione, (5), showed the greatest inhibitory activity.