
Journal of Heterocyclic Chemistry p. 1063 - 1066 (1996)
Update date:2022-08-17
Topics:
Rigo, Benoit
Dolaine, Regis
El Ghammarti, Samira
Couturier, Daniel
While methyl N-(4-nitrobenzyl)pyroglutamate can be obtained from methyl-N-trimethylsilylpyroglutamate, the best way to obtain methyl N-(2-nitrobenzyl)pyroglutamate is to react 4-nitro benzyl bromide with the iminoether derived from methyl pyroglutamate.
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