An efficient synthesis of pyrrolo[2,1-c][1,4]benzodiazepine antibiotics via reductive cyclization

DOI: 10.1016/S0960-894X(97)00314-4

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1825 - 1828 (1997)

Update date:2022-08-10

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Authors:

Kamal, Ahmed

Reddy, B. S. Nararyan

Reddy, B. S. Praveen

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Article abstract of DOI:10.1016/S0960-894X(97)00314-4

A new and convenient one-pot synthesis of pyrrolo[2,1-c][1,4]benzodiazepine (PBD) ring system has been achieved by a reductive cyclization employing N,N-dimethylhydrazine and FeCl₃.6H₂O in good yields.

Full text of DOI:10.1016/S0960-894X(97)00314-4

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Product name:L-Proline, 1-(2-nitrobenzoyl)-, methyl ester

Cas No:105089-64-3

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