Convenient preparation of di- and tri-ethynylbenzenes by cleavage of 2-hydroxy-2-methylbut-3-yn-4-yl-benzenes with water miscible reagents

Article abstract of DOI:10.1080/00397919608004542

2-Hydroxy-2-methylbut-3-yn-4-yl-benzenes, readily available from bromobenzenes, are efficiently cleaved by the water-miscible reagents sodium 2-propoxide in 2-propanol, or potassium hydroxide in dioxan, which facilitatese isolation of volatile ethynylbenzenes.

Full text of DOI:10.1080/00397919608004542

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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Convenient Preparation of
Di- and Tri-Ethynylbenzenes
by Cleavage of 2-Hydroxy-2-
methylbut-3-yn-4-ylbenzenes
with Water Miscible Reagents
J. A. Hugh MacBride a & Kenneth Wade a
a Chemistry Department , Durham University , South
Road, Durham, DH1 3LE, (UK)
Published online: 23 Aug 2006.
To cite this article: J. A. Hugh MacBride & Kenneth Wade (1996) Convenient
Preparation of Di- and Tri-Ethynylbenzenes by Cleavage of 2-Hydroxy-2-methylbut-3-
yn-4-ylbenzenes with Water Miscible Reagents, Synthetic Communications: An
International Journal for Rapid Communication of Synthetic Organic Chemistry, 26:12,
2309-2316, DOI: 10.1080/00397919608004542
To link to this article: http://dx.doi.org/10.1080/00397919608004542
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