Selectivity in bromination of aniline and N-substituted anilines encapsulated in β-cyclodextrin

Article abstract of DOI:10.1016/0040-4020(96)00027-0

In contrast to the conventional bromination, aniline and N-methylaniline encapsulated in β-Cyclodextrin (β-CD) give ortho-bromoaniline and parabromo-N-methylaniline respectively in larger yield. The results are explained on the basis of mode of complexation between β-CD and anilines.