ALKYLATIONS EN ABSENCE DE SOLVANT ORGANIQUE. EFFETS D'ADDITION D'OXYDES MINERAUX ET DE SELS D'AMMONIUM - I. N-ALKYLATION DE L'INDOLE EN MILIEU BASIQUE

DOI: 10.1016/S0040-4020(01)91976-3

Source and publish data:

Tetrahedron p. 2669 - 2672 (1983)

Update date:2022-08-11

Topics:

Authors:

Barry, J.

Bram, G.

Decodts, G.

Loupy, A.

Pigeon, P.

Sansoulet, J.

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Article abstract of DOI:10.1016/S0040-4020(01)91976-3

Indole alkylation, after anion formation (KOH+1percent NBu4Br) is achieved without any solvent in the presence or in the absence of solid mineral supports.N-Ethyl or octyl derivatives are thus obtained quantitatively under very mild conditions.

Full text of DOI:10.1016/S0040-4020(01)91976-3

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