A concise access to a new class of selective anti-inflammatory steroid derivatives

DOI: 10.1016/S0040-4039(97)10809-7

Source and publish data:

Tetrahedron Letters p. 1173 - 1174 (1998)

Update date:2022-08-11

Topics:

Authors:

Quiclet-Sire, Beatrice

Zard, Samir Z.

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Article abstract of DOI:10.1016/S0040-4039(97)10809-7

The 17β-thiomethyl-16α,17α-ketal motif of a new class of selective anti-inflammatory androstane derivatives useful in the treatment of asthma is readily constructed by a new radical degradation of the corticosteroid side chain.

Full text of DOI:10.1016/S0040-4039(97)10809-7

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