Facile conversion of N6-benzoyladenosines into 5'-chloro-5'-deoxy-8-hydroxyadenosines by a reaction with cupric chloride: A prominent substituent effect of the N6-benzoyl group

DOI: 10.1248/cpb.39.1902

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1902 - 1904 (1991)

Update date:2022-08-05

Topics:

Authors:

Kitade Kitade

Nakanishi

Sako Sako

Hirota Hirota

Maki Maki

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.39.1902

Facile conversion of N⁶-benzoyl-2',3'-O-isopropylideneadenosine into N⁶-benzoyl-5'-chloro-5'-deoxy-8-hydroxy-2',3'-O-isopropylideneadenosine by a reaction with cupric chloride in acetonitrile provides a new method for the chemical modification of adenosines. This reflects the prominent substituent effect of N⁶-benzoyl group on the chemical reactivity of adenosines.

Full text of DOI:10.1248/cpb.39.1902

NII-Electronic Library Service

Products guided by the article

Product name:N⁶-benzoyl-5'-O,8-cyclo-2',3'-O-isopropylideneadenosine

Cas No:107855-22-1

R&D Labs maybe for 107855-22-1

Taiwan Surfactant Corp.

Contact:886 2 2541 0022

Address:8 Fl., No. 11, Sec. 1, Chung Shan North Rd., Taipei, Taiwan R.O.C.
Tianjin Te-An Chemtech Co., Ltd.(expird)

Contact:+86-22-65378638

Address:A5-8, No.80 Haiyun Street, TEDA
SNC | GOOD FORTUNE

Contact:0086-22-2822 1962 / 2822 1963

Address:B-808, No. 1, North-South Street, Hexi District,
Suzhou SuKaiLu Chemical Technology Co., Ltd.

Contact:+86-512-62766020

Address:Floor 4, Building 1, Xinyi Pharmaceutical Valley Wisdom Industrial Park, 415 Changyang Street, Suzhou Industrial Park, Jiangsu Province
Zhengzhou HQ Material Co.,Ltd

Contact:+86-371-67759225

Address:No.32, Jinsuo Road, High-tech Zone

Relevant to this article

Removal of metal-metal bonding in a dimetallic paddlewheel complex: Molecular and electronic structure of bis(phenyl) dirhodium(III) carboxamidate compounds

Doi:10.1021/om800631b
(2008)
THE SYNTHESIS AND PHARMACOLOGY OF SOME SUBSTITUTED 1,3-BENZODIOXOLES

Doi:10.1021/jm00325a017
(1965)
A synthetic approach to the communesins

Doi:10.1055/s-2008-1078251
(2008)
Sulfur, oxygen, and nitrogen mustards: Stability and reactivity

Doi:10.1039/c2ob26482j
(2012)
Regioselective synthesis of benzimidazole thiophene inhibitors of polo-like kinase 1

Doi:10.1016/j.tetlet.2008.08.077
(2008)
Doi:10.1007/BF01153882
(1961)

Article Doi