Copper-catalyzed conjugate addition of organomagnesium reagents to α,β-ethylenic esters: A simple high yield procedure

Article abstract of DOI:10.1016/S0040-4039(00)88506-8

The conjugate addition of organomagnesium reagents to α, β-ethylenic esters is performed in THF, at room temperature (30 min to 1.5 h), in the presence of CuCl (3%) and Me₃SiCl (1.2 eq.). Good yields of 1,4-addition products are obtained according to this very simple procedure.