Bulletin of the Chemical Society of Japan p. 262 - 266 (1992)
Update date:2022-08-11
Topics:
Takahashi, Kyoko
Shibagaki, Makoto
Matsushita, Hajime
The reduction of dicarboxylic acid anhydrides with 2-propanol proceeded efficiently over hydrous zirconium oxide to give the corresponding lactones and cyclic ethers.Secondary and primary alcohols, with the exception of methanol, are able to act as hydride donors in this reduction.The reduction proceeded as nearly second order concerning the concentration of 2-propanol and minus order concerning that of acid anhydride.These results suggest that the reduction was preferred under lower concentrations of acid anhydride and higher concentrations of 2-propanol.The selectivity of lactone or ether could be changed by the reaction temperature or the molar ratio of dicarboxylic acid anhydride to alcohol.
View MoreContact:86-27-84888681
Address:Wuhan economic & technology development zone
Zhejiang Genebest Pharmaceutical Co.,Ltd.
Contact:0086-571-63532866
Address:No.1 Jinboshi Rd Lishan Town Fuyang City Zhejiang Province China
Lanzhou huibang biological chemical technology Co., LTD
Contact:0931-7843964
Address:NO.2011,Yannan Road,Chengguan,
website:http://www.u-chemo.com
Contact:+86-21-61558312
Address:Dong Fang Road,
Hangzhou Zyter Biological & Chemical Technology Co., Ltd.
website:http://www.zyterpharm.com
Contact:+86-18858184290
Address:West Wenyi Road, Cangqian, Yuhang
Doi:10.1021/jacs.9b07084
(2019)Doi:10.1055/s-1975-23811
(1975)Doi:10.1016/S0040-4020(01)80205-2
(1993)Doi:10.1016/j.chempr.2019.10.022
(2020)Doi:10.1006/jcat.1995.1135
(1995)Doi:10.1002/anie.201408576
(2014)